Simparica TRIO Chewable

Prescription Required

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All medications are filled by Pet's Choice Pharmacy. More information. Can only be shipped in the United States.
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Product Summary:

Prescription items are NON-RETURNABLE and NON REFUNDABLE


Simparica Trio Chewable


Simparica Trio makes it simple to deliver the protection every best friend deserves.

Simparica Trio is the first monthly chewable to protect dogs against heartworm disease, five types of ticks, fleas, roundworms and hookworms, all in one monthly chewable. Simparica Trio works to get rid of ticks and fleas on dogs fast. It starts to kill deer ticks within 8 hours, and fleas within 4 hours.


·      Protects dogs against heartworm disease, ticks & fleas, roundworms & hookworms

·      Demonstrated safe for puppies as young as 8 weeks old, weighing at least 2.8 lbs

·      Tasty chewable that you only need to give once a month

·      FDA-approved and available with a vet’s prescription



This medication should be given orally each month.

Consult your veterinarian for proper dosing instructions.


Storage Instructions

Store at or below 30°C (86°F).


Possible Side Effects

The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea.



If a dose is missed, a new dose should be given immediately. If a dose is vomited or spit out, a new dose should be given again. Then, continue the prescribed monthly dosing schedule.



Style Item Number Model Number UPC
2.8-5.5lb Gold 1 Count PX101148 55 001 012ZOE-22678-1
5.6-11lb Purple 1 Count PX101148 11 001 012ZOE-22679-1
11.1-22lb Caramel 1 Count PX101148 22 001 012ZOE-22680-1
22.1-44lb Teal 1 Count PX101148 44 001 012ZOE-22681-1
44.1-88lb Green 1 Count PX101148 88 001 012ZOE-22682-1
88.1-132lb Brown 1 Count PX101148 132 001 012ZOE-22683-1
2.8-5.5lb Gold 6 Count PX101148 55 006 012ZOE-22678-1
5.6-11lb Purple 6 Count PX101148 11 006 012ZOE-22679
11.1-22lb Caramel 6 Count PX101148 22 006 012ZOE-22680 087219131589
22.1-44lb Teal 6 Count PX101148 44 006 012ZOE-22681
44.1-88lb Green 6 Count PX101148 88 006 012ZOE-22682
88.1-132lb Brown 6 Count PX101148 132 006 012ZOE-22683

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Additional Information:

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states.  We are only authorized to ship within the United States.  

To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety. By law we can only accept a prescription faxed from your veterinarian or we must have the original prescription.

All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US. Prescription products cannot be returned.  

Are we a licensed pharmacy?

The National Association of Boards of Pharmacy (NABP) has approved us as a Safe Site through its .pharmacy verified website program. We are not a licensed pharmacy; however, we are permitted to display pet medications on our site and have prescription orders fulfilled and delivered through our trusted partner, Pet’s Choice Pharmacy, an NABP .pharmacy verified website. This gives you a trusted and affordable alternative to purchase the medications your beloved pets need to maintain quality of life and overall health.

The .Pharmacy Verified program, prior to approval of domain registration, ensures that applicants meet all applicable Program Standards, which address regulatory standards including; to be licensed, registered, or hold appropriate permits where it is headquartered and where its customers reside, to protect patient medical and financial information and to have a clean disciplinary record.

To find out How to Fill your Pets Prescription click on More Information at the top. 

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