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dog.com > Pharmacy > Medications > Item # P00380

Mexiletine Capsule 200mg 100 Count

Prescription Required
$105.99
Regularly: $119.99
Today's savings: 12%
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ITEM OUR PRICE
Mexiletine Capsule 200mg 100 Count

$105.99

In Stock. Usually Ships in 2-3 weeks.

Shipping weight = 0.08 lb.

All medications are filled by Pet's Choice Pharmacy. More information. Can only be shipped in the United States.
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This item is Special Order. Please allow additional processing time. In some cases, processing time can take up to 2 weeks. Special order items cannot be cancelled once ordered by pharmacy. 

 


Product Summary:

Mexiletine Capsule
 
Mexiletine is a class 1B, sodium channel blocker, anti-arrhythmia drug, used to treat chronic ventricular arrhythmias in the dogs. Mexiletine is used to treat ventricular arrhythmias including PVC’s and ventricular tachycardia.
 
Mexiletine is well absorbed orally. It is primarily excreted in the urine although approximately 10% is metabolized by the liver and excreted in the feces. The half-life of this drug may be prolonged in animals with reduced cardiac output, or after an acute myocardial infarction. The half-life may also be prolonged in animals with hepatic dysfunction or severe kidney disease.
 
The most commonly used oral drugs for the chronic treatment of ventricular arrhythmias are atenolol, sotalol, procainamide, amiodarone, and mexiletine. Mexiletine may be combined with either atenolol or sotalol in instances when monotherapy is not adequate. Mexiletine may be used to treat inherited cardiomyopathy in Boxers and dilated cardiomyopathy in Doberman pinschers. A positive response to therapy would be an 85% reduction of ventricular premature contractions. The complete elimination of ventricular arrhythmia is not considered a realistic goal.
 
For Use In:
Dogs

Side Effects

  • The most common side effects are related to the GI tract including nausea and vomiting. Giving food with mexiletine has been shown to decrease the incidence of GI side effects.
  • Other possible side effects include central nervous system signs such as dizziness, loss of balance and trembling, shortness of breath, and cardiac signs including PVCs or chest pain.
  • Rare side effects reported in humans include seizures, and bone marrow suppression.

Precautions

  • Mexiletine should be used with extreme caution in animals with the following conditions: 2nd or 3rd degree AV heart block, intraventricular conduction abnormality, sinus node function abnormality, cardiogenic shock, congestive heart failure, myocardial infarction, liver dysfunction, hypotension, or seizure disorders.

Drug Interactions

  • Concurrent use with lidocaine increases the likelihood of adverse effects.
  • There are a number of drugs that may cause drug interactions either through changing the rate of absorption or changing the rate of metabolism of mexiletine. This list includes: antacids, atropine, opiates, cimetidine, griseofulvin, metoclopramide, phenobarbital, phenytoin, primidone, rifampin, theophylline.
  • Drugs which change urinary acidity may affect the renal excretion of mexiletine. These drugs include methionine, ammonium chloride, potassium phosphate, sodium phosphate, citrates, sodium bicarbonate, and carbonic anhydrase inhibitors.

Overdose

Overdose with mexiletine carries a significant risk of toxicity. It is reported in the human literature that central nervous system signs precede cardiovascular signs. In experimental work in dogs, a four fold overdose consistently produced CNS signs within 10 minutes of oral administration. If recognized in time, GI emptying protocol should be attempted in conjunction with urinary acidification and supportive care.
Item Number Model Number UPC
P00380 012KV-30025 300938740017
Additional Information:

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states, excluding North Carolina. Pet’s Choice is actively working with North Carolina Board of Pharmacy and expect to be licensed to fill prescriptions in 2018. We can only ship to US states. 

 

To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety.

 

All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US.

Prescription products cannot be returned.  


How do you fill my pet’s prescription order?

We understand how important your pet’s health is to you. That’s why we partnered with Pet’s Choice Pharmacy, a fully accredited Vet-VIPPS national pharmacy. Located in Belleville, Kansas, Pet’s Choice Pharmacy is a trusted partner that is fully licensed to distribute pharmaceutical products in all states, excluding North Carolina. This licensing ensures that they adhere to the proper standards for handling and dispensing pet medications directly to you, at a significant savings.

 

How does the prescription process happen?

Pet’s Choice Pharmacy will contact your veterinarian directly to obtain the necessary information and approval to dispense the medications ordered. It is helpful to have veterinarian’s name, phone number, and fax number when you place your order so we can speed up contact process with veterinarian. After prescription is verified, your medication will be safely dispensed and shipped directly to you. If you veterinarian does not participate or support online sales, you can mail your script to us directly.

Pet’s Choice Pharmacy  

814 K Street

Belleville, KS 66935

KVSupply.com Order #

 

Are we a licensed pharmacy?

The National Association of Boards of Pharmacy (NABP) has approved us as an Internet Advertiser of prescription drug-related services through its e-Advertiser Approval program. We are not a licensed pharmacy; however, we are permitted to display pet medications on our site and have prescription orders fulfilled and delivered through our trusted partner, Pet’s Choice Pharmacy, a full Vet-VIPPS accredited pharmacy. This gives you a trusted and affordable alternative to purchase the medications your beloved pets need to maintain quality of life and overall health.

If you have any medical questions about your pet, we suggest you speak with your veterinarian before administering any medication.  If you would like to speak with our pharmacy support team about your order, you can contact us directly Monday-Friday 9 am-5 pm EST at (877) 574-2267. If you veterinarian needs to fax your prescription, our fax number is (866) 787-1177.

 

** By law we can only accept a prescription faxed from your veterinarian or we must have the original prescription**

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