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Comfortis 6pk Dogs

Prescription Required
From $76.49


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All medications are filled by Pet's Choice Pharmacy. More information. Can only be shipped in the United States.
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Product Summary:

Prescription items are NON-RETURNABLE and NON REFUNDABLE

 Comfortis Chewable Tablet
Comfortis is the first FDA-approved, chewable, beef-flavored tablet that kills fleas and prevents flea infestations on dogs for a full month.
Comfortis is used to treat and prevent flea infestations.
For use:
Dogs at least 14 weeks old
XXSmall (Yellow) - Dogs 3.3-4.9 lbs/Cats 2-4 lbs
XSmall (Pink) - Dogs 5-10 lbs/Cats 4.1-6 lbs
Small (Orange) - Dogs 10.1-20 lbs/Cats 6.1-12 lbs
Medium (Green) - Dogs 20.1-40 lbs/Cats 12.1-24 lbs
Large (Blue) - Dogs 40.1-60 lbs
XLarge (Brown) - Dogs 60.1-120 lbs
Active ingredient(s):
The safety of Comfortis has not been established in breeding, pregnant, or lactating animals. Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Allergic reactions to medications may occur. Be sure to inform your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Side effects:
Side effects may include nausea, vomiting, diarrhea, loss of appetite, and decreased activity. If you notice anything unusual, contact your veterinarian.
Comfortis should be given orally as directed by your veterinarian. If vomiting occurs within an hour of administration, redose with another full dose.
Style Item Number Model Number UPC
40 to 60 lbs 496941 LG 012LLY-40-1-60 309864225063
20 to 40 lbs 496941 MD 012LLY-20-1-40 309864224066
10 to 20 lbs 496941 SM 012LLY-10-1-20 309864223069
60 to 120 lbs 496941 XL 012LLY-61-1-120 309864227067
5 to 10 lbs 496941 XS 012LLY-5-10 309864222062
3.3-4.9 lbs 496941 XXS 012LLY-3-3-4-9 309864221065
Additional Information:

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states, excluding North Carolina. Pet’s Choice is actively working with North Carolina Board of Pharmacy and expect to be licensed to fill prescriptions in 2018. We can only ship to US states. 


To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety.


All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US.

Prescription products cannot be returned.  

How do you fill my pet’s prescription order?

We understand how important your pet’s health is to you. That’s why we partnered with Pet’s Choice Pharmacy, a fully accredited Vet-VIPPS national pharmacy. Located in Belleville, Kansas, Pet’s Choice Pharmacy is a trusted partner that is fully licensed to distribute pharmaceutical products in all states, excluding North Carolina. This licensing ensures that they adhere to the proper standards for handling and dispensing pet medications directly to you, at a significant savings.


How does the prescription process happen?

Pet’s Choice Pharmacy will contact your veterinarian directly to obtain the necessary information and approval to dispense the medications ordered. It is helpful to have veterinarian’s name, phone number, and fax number when you place your order so we can speed up contact process with veterinarian. After prescription is verified, your medication will be safely dispensed and shipped directly to you. If you veterinarian does not participate or support online sales, you can mail your script to us directly.

Pet’s Choice Pharmacy  

814 K Street

Belleville, KS 66935 Order #


Are we a licensed pharmacy?

The National Association of Boards of Pharmacy (NABP) has approved us as an Internet Advertiser of prescription drug-related services through its e-Advertiser Approval program. We are not a licensed pharmacy; however, we are permitted to display pet medications on our site and have prescription orders fulfilled and delivered through our trusted partner, Pet’s Choice Pharmacy, a full Vet-VIPPS accredited pharmacy. This gives you a trusted and affordable alternative to purchase the medications your beloved pets need to maintain quality of life and overall health.

If you have any medical questions about your pet, we suggest you speak with your veterinarian before administering any medication.  If you would like to speak with our pharmacy support team about your order, you can contact us directly Monday-Friday 9 am-5 pm EST at (877) 574-2267. If you veterinarian needs to fax your prescription, our fax number is (866) 787-1177.


** By law we can only accept a prescription faxed from your veterinarian or we must have the original prescription**

Product Reviews by Customers

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Browse 3 questions Browse 3 questions and 7 answers
Why did you choose this? Store
because its only one that works for us
Deborah H on Jan 2, 2019
I ordered Comfortis for small dogs 10lbs or under
Lynn S on Nov 21, 2018
because its only one that works for us
Deborah H on Jan 2, 2019
This product works well for my pups and they think they are getting a treat.
JODY A on Dec 3, 2018
I ordered Comfortis for small dogs 10lbs or under
Lynn S on Nov 21, 2018
You have everything that I need to keep my pets healthy.
Linda R on May 31, 2017
Vet Recommended
Ann B on Feb 15, 2015
This product works well for my pups and they think they are getting a treat.
JODY A on Dec 3, 2018
You have everything that I need to keep my pets healthy.
Linda R on May 31, 2017
can I use this for a large cat, 25 lbs?
A shopper on Jun 17, 2017
BEST ANSWER: I apologize, Comfortis labeling only goes to 24 pounds, which is the Medium (green) box. I would consult your veterinarian to see what he or she recommends. Good luck!
can I buy this product without prescription?
A shopper on Apr 4, 2017
BEST ANSWER: Hello, this item does require a prescription from vet to be ordered.