Betagen Topical Spray

Prescription Required

Eligible for free e-certification with purchase

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In Stock. Usually Ships in 2-3 weeks.



In Stock. Usually Ships 3-6 business days.

Shipping weight = 0.50 lb.


All medications are filled by Pet's Choice Pharmacy. More information. Can only be shipped in the United States.
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Product Summary:

Prescription items are NON-RETURNABLE and NON REFUNDABLE
***60ml-CURRENT EXPIRATION DATE 09/2021*** 
***240ml-CURRENT EXPIRATION DATE 08/2021*** 

Betagen Topical Spray


For the treatment of infected superficial lesions in dogs caused by bacteria sensitive to gentamicin.

Each mL contains: gentamicin sulfate equivalent to 0.57 mg gentamicin base betamethasone valerate equivalent to 0.284 mg betamethasone 163 mg isopropyl alcohol propylene glycol methylparaben and propylparaben as preservatives purified water q.s. Hydrochloric acid may be added to adjust pH.

For Topical Use:

Dogs Only




Use as Directed by your Veterinarian


Gentamicin is a mixture of aminoglycoside antibiotics derived from the fermentation of Micromonospora purpurea. Gentamicin sulfate is a mixture of sulfate salts of the antibiotics produced in this fermentation. The salts are weakly acidic and freely soluble in water.
Gentamicin sulfate contains not less than 500 micrograms of gentamicin base per milligram.
Betamethasone valerate is a synthetic glucocorticoid.

Gentamicin a broad-spectrum antibiotic is a highly effective topical treatment for bacterial infections of the skin. In vitro gentamicin is bactericidal against a wide variety of gram-positive and gram-negative bacteria isolated from domestic animals. 1 2 Specifically gentamicin is active against the following organisms isolated from canine skin: Alcaligenes sp. Citrobacter sp. Klebsiella sp. Pseudomonas aeruginosa indole-positive and negative Proteus sp. Escherichia coli Enterobacter sp. Staphylococcus sp. and Streptococcus sp.
Betamethasone valerate emerged from intensive research as the most promising of some 50 newly synthesized corticosteroids in the experimental model described by McKenzie3 et al. This human bioassay technique has been found reliable for evaluating the vasoconstrictor properties of new topical corticosteroids and is useful in predicting clinical efficacy.
Betamethasone valerate in veterinary medicine has been shown to provide anti-inflammatory and antipruritic activity in the topical management of corticosteroid responsive infected superficial lesions in dogs.

Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia fetal death retained placenta and metritis.
Additionally corticosteroids administered to dogs rabbits and rodents during pregnancy have produced cleft palate. Other congenital anomalies including deformed forelegs phocomelia and anasarca have been reported in offspring of dogs which received corticosteroids during pregnancy.

If hypersensitivity to any of the components occurs treatment with this product should be discontinued and appropriate therapy instituted.

Gentamicin sulfate with betamethasone valerate topical spray was well tolerated in an abraded skin study in dogs. No treatment-related toxicological changes in the skin were observed.
Systemic effects directly related to treatment were confined to histological changes in the adrenals liver and kidney and to organ-to-body weight ratios of adrenals. All were dose related were typical for or not unexpected with corticosteroid therapy and were considered reversible with cessation of treatment.

Side effects such as SAP and SGPT enzyme elevations weight loss anorexia polydipsia and polyuria have occurred following parenteral or systemic use of synthetic corticosteroids in dogs. Vomiting and diarrhea (occasionally bloody) have been observed in dogs.
Cushings syndrome in dogs has been reported in association with prolonged or repeated steroid therapy.

Antibiotic susceptibility of the pathogenic organism(s) should be determined prior to the use of this preparation. Use of topical antibiotics may permit overgrowth of non-susceptible bacteria fungi or yeasts. If this occurs treatment should be instituted with other appropriate agents as indicated.
Administration of recommended dose beyond 7 days may result in delayed wound healing. Animals treated longer than 7 days should be monitored closely.
Avoid ingestion. Oral or parenteral use of corticosteroids depending on dose duration and specific steroid may result in inhibition of endogenous steroid production following drug withdrawal.
In patients presently receiving or recently withdrawn from systemic corticosteroid treatments therapy with a rapidly acting corticosteroid should be considered in especially stressful situations.
If ingestion should occur patients should be closely observed for the usual signs of adrenocorticoid overdosage which include sodium retention potassium loss fluid retention weight gains polydipsia and/or polyuria. Prolonged use or overdosage may produce adverse immunosuppressive effects.

Store upright between 2°C and 30°C (36°F and 86°F).

ANADA #200-188 Approved by FDA.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Style Item Number Model Number UPC
60ml 496490 060 012SCH01-60 357319551540
240ml 496490 240 012SCH01-240 357319551694

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Additional Information:

Please Note: 

This prescription product or therapeutic food is fulfilled by Pet’s Choice Pharmacy, Inc. A licensed pharmacy in all states.  We are only authorized to ship within the United States.  

To order prescription products or therapeutic foods must have an existing, valid veterinarian-client-patient relationship.  Prescription requests are subject to a Drug Utilization Review by a licensed pharmacist for patient safety. By law we can only accept a prescription faxed from your veterinarian or we must have the original prescription.

All prescription products (excluding therapeutic food) are FDA approved, or EPA licensed, to be sold in the US. Prescription products cannot be returned.  

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The National Association of Boards of Pharmacy (NABP) has approved us as a Safe Site through its .pharmacy verified website program. We are not a licensed pharmacy; however, we are permitted to display pet medications on our site and have prescription orders fulfilled and delivered through our trusted partner, Pet’s Choice Pharmacy, an NABP .pharmacy verified website. This gives you a trusted and affordable alternative to purchase the medications your beloved pets need to maintain quality of life and overall health.

The .Pharmacy Verified program, prior to approval of domain registration, ensures that applicants meet all applicable Program Standards, which address regulatory standards including; to be licensed, registered, or hold appropriate permits where it is headquartered and where its customers reside, to protect patient medical and financial information and to have a clean disciplinary record.

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