Be sure to select the proper dosage based on your dogs body weight. Use at the rate of 2-4 grams (2-4cc) for every 30 lbs. of body weight. Turn dial until the lead edge of the dial aligns with proper dosage mark on the plunger shaft. Uncap syringe and place tip on the back of the tongue. Depress plunger until it stops. Wipe syringe down with a paper towel and recap it. Do not refrigerate. 3 year shelf life.