Prednisolone is a steroid that works by blocking the release of substances in the body that cause inflammation and allergic actions.
Prednisolone is used to relieve inflamed areas, decrease swelling, redness, itching, allergic reactions and for supportive care during periods of stress.
Dogs, cats & horses
This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals. Do not use this medication if your pet has a fungal infection anywhere in the body, certain types of mange, Cushing's disease, stomach ulcers, or high blood pressure. Steroid medication can weaken your pet's immune system, making it easier for them to get an infection or worsening an infection they already have or have recently had. Do not administer a "live" vaccine while using prednisolone. Do not stop giving your pet prednisolone suddenly, or they could have unpleasant withdrawal symptoms. Ask your veterinarian how to avoid withdrawal symptoms. The safety of this medication has not been evaluated in pregnant, breeding, or nursing animals. Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. The following drugs can potentially interact with prednisolone: amphotericin B, potassium depleting diuretics, digitalis glycosides, salicylates, insulin, phenytoin, phenobarbital, rifampin, cyclosporine, cyclophosphamide, mitotane, non-steroidal anti-inflammatory drugs, and anticholinesterase agents. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Possible side effects may include excessive thirst, excessive ingestion of food, excessive urination, dull, dry haircoat, weight gain, panting, vomiting, diarrhea, stomach upset, muscle wasting, depression, lethargy, viciousness. If symptoms persist and appear troublesome, contact your veterinarian. Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Prednisolone should be given orally as directed by your veterinarian. Try to give this medication at about the same time each day, preferably with or after a meal.
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